| PICO/Mini-CAT | Question |
| 1 | In adults with functional constipation, does modified toileting posture compared with standard toilet positioning improve bowel evacuation and straining symptoms? |
| 2 | In adults w/ chronic insomnia, does using a weighted blanket compared w/ standard blanket improve insomnia severity, reduce nighttime awakenings, and objective sleep parameters? |
| 3 | In adults who are overweight or obese, does time-restricted eating compared with traditional calorie counting result in greater weight loss and improvements in metabolic health? |
